| 1 | 13/9/2020 | 223-1 v FC GroningenFC Groningen 1-3 PSV Eindhoven | Dutch Eredivisie |
| 2 | 19/9/2020 | 222-1 v FC EmmenPSV Eindhoven 2-1 FC Emmen | Dutch Eredivisie |
| 3 | 24/9/2020 | 22 5-1 v Mura Murska SobotaMura Murska Sobota 1-5 PSV Eindhoven | Europa League Third Qualifying Round |
| 4 | 27/9/2020 | 221-1 v Heracles AlmeloHeracles Almelo 1-1 PSV Eindhoven | Dutch Eredivisie |
| 5 | 1/10/2020 | 22 2-0 v RosenborgRosenborg 0-2 PSV Eindhoven | Europa League Qualifying Play-off Round |
| 6 | 4/10/2020 | 222-0 v Fortuna SittardPSV Eindhoven 2-0 Fortuna Sittard | Dutch Eredivisie |
| 7 | 18/10/2020 | 223-0 v PEC ZwollePEC Zwolle 0-3 PSV Eindhoven | Dutch Eredivisie |
| 8 | 22/10/2020 | 221-2 v GranadaPSV Eindhoven 1-2 Granada | Europa League Group E |
| 9 | 8/11/2020 | 223-0 v Willem IIPSV Eindhoven 3-0 Willem II | Dutch Eredivisie |
| 10 | 22/11/2020 | 221-1 v FC TwenteFC Twente 1-1 PSV Eindhoven | Dutch Eredivisie |
| 11 | 26/11/2020 | 22 3-2 v PAOK FCPSV Eindhoven 3-2 PAOK FC | Europa League Group E |
| 12 | 29/11/2020 | 221-0 v Sparta RotterdamPSV Eindhoven 1-0 Sparta Rotterdam | Dutch Eredivisie |
| 13 | 3/12/2020 | 221-0 v GranadaGranada 0-1 PSV Eindhoven | Europa League Group E |
| 14 | 6/12/2020 | 22 2-2 v sc Heerenveensc Heerenveen 2-2 PSV Eindhoven | Dutch Eredivisie |
| 15 | 10/12/2020 | 22 4-0 v Omonia NicosiaPSV Eindhoven 4-0 Omonia Nicosia | Europa League Group E |
| 16 | 13/12/2020 | 22 2-1 v FC UtrechtPSV Eindhoven 2-1 FC Utrecht | Dutch Eredivisie |
| 17 | 19/12/2020 | 224-1 v RKC WaalwijkRKC Waalwijk 1-4 PSV Eindhoven | Dutch Eredivisie |
| 18 | 22/12/2020 | 224-1 v VVV VenloPSV Eindhoven 4-1 VVV Venlo | Dutch Eredivisie |
| 19 | 10/1/2021 | 222-2 v AjaxAjax 2-2 PSV Eindhoven | Dutch Eredivisie |
| 20 | 13/1/2021 | 22 1-3 v AZ AlkmaarPSV Eindhoven 1-3 AZ Alkmaar | Dutch Eredivisie |
| 21 | 16/1/2021 | 225-3 v Sparta RotterdamSparta Rotterdam 3-5 PSV Eindhoven | Dutch Eredivisie |
| 22 | 23/1/2021 | 222-0 v RKC WaalwijkPSV Eindhoven 2-0 RKC Waalwijk | Dutch Eredivisie |
| 23 | 26/1/2021 | 222-0 v FC EmmenFC Emmen 0-2 PSV Eindhoven | Dutch Eredivisie |
| 24 | 31/1/2021 | 221-3 v FeyenoordFeyenoord 3-1 PSV Eindhoven | Dutch Eredivisie |
| 25 | 6/2/2021 | 223-0 v FC TwentePSV Eindhoven 3-0 FC Twente | Dutch Eredivisie |
| 26 | 13/2/2021 | 222-2 v ADO Den HaagADO Den Haag 2-2 PSV Eindhoven | Dutch Eredivisie |
| 27 | 18/2/2021 | 222-4 v OlympiakosOlympiakos 4-2 PSV Eindhoven | Europa League Round of 32 |
| 28 | 21/2/2021 | 223-1 v VitessePSV Eindhoven 3-1 Vitesse | Dutch Eredivisie |
| 29 | 25/2/2021 | 22 2-1 v OlympiakosPSV Eindhoven 2-1 Olympiakos | Europa League Round of 32 |
| 30 | 28/2/2021 | 22 1-1 v AjaxPSV Eindhoven 1-1 Ajax | Dutch Eredivisie |
| 31 | 7/3/2021 | 223-1 v Fortuna SittardFortuna Sittard 1-3 PSV Eindhoven | Dutch Eredivisie |
| 32 | 14/3/2021 | 221-1 v FeyenoordPSV Eindhoven 1-1 Feyenoord | Dutch Eredivisie |
| 33 | 21/3/2021 | 220-2 v AZ AlkmaarAZ Alkmaar 2-0 PSV Eindhoven | Dutch Eredivisie |
| 34 | 4/4/2021 | 223-0 v Heracles AlmeloPSV Eindhoven 3-0 Heracles Almelo | Dutch Eredivisie |
| 35 | 11/4/2021 | 222-0 v VVV VenloVVV Venlo 0-2 PSV Eindhoven | Dutch Eredivisie |
| 36 | 24/4/2021 | 22 1-0 v FC GroningenPSV Eindhoven 1-0 FC Groningen | Dutch Eredivisie |
| 37 | 9/5/2021 | 22 2-0 v Willem IIWillem II 0-2 PSV Eindhoven | Dutch Eredivisie |
| 38 | 13/5/2021 | 224-2 v PEC ZwollePSV Eindhoven 4-2 PEC Zwolle | Dutch Eredivisie |
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