| 1 | Sat 8 Aug | 322-2 v Fortuna SittardPSV Eindhoven 2-2 Fortuna Sittard | Dutch Eredivisie |
| 2 | Sat 15 Aug | 322-1 v Excelsior RotterdamExcelsior Rotterdam 1-2 PSV Eindhoven | Dutch Eredivisie |
| 3 | Sun 23 Aug | 325-1 v FC GroningenPSV Eindhoven 5-1 FC Groningen | Dutch Eredivisie |
| 4 | Sun 30 Aug | 326-1 v FC UtrechtFC Utrecht 1-6 PSV Eindhoven | Dutch Eredivisie |
| 5 | Sat 5 Sep | 323-1 v AjaxAjax 1-3 PSV Eindhoven | Dutch Eredivisie |
| 6 | Thu 10 Sep | 321-1 v Shakhtar DonetskPSV Eindhoven 1-1 Shakhtar Donetsk | UEFA Champions League Matchday 1 |
| 7 | Sun 13 Sep | 324-1 v Sparta RotterdamPSV Eindhoven 4-1 Sparta Rotterdam | Dutch Eredivisie |
| 8 | Sun 20 Sep | 322-3 v FC TwenteFC Twente 3-2 PSV Eindhoven | Dutch Eredivisie |
| 9 | Fri 9 Oct | 322-0 v sc HeerenveenPSV Eindhoven 2-0 sc Heerenveen | Dutch Eredivisie |
| 10 | Tue 13 Oct | 320-1 v RB LeipzigRB Leipzig 1-0 PSV Eindhoven | UEFA Champions League Matchday 2 |
| 11 | Sat 17 Oct | 321-2 v ADO Den HaagADO Den Haag 2-1 PSV Eindhoven | Dutch Eredivisie |
| 12 | Tue 20 Oct | 321-0 v FC PortoFC Porto 0-1 PSV Eindhoven | UEFA Champions League Matchday 3 |
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