| 1 | Sat 10 Aug | 325-1 v RKC WaalwijkPSV Eindhoven 5-1 RKC Waalwijk | Dutch Eredivisie |
| 2 | Sun 18 Aug | 323-1 v Heracles AlmeloHeracles Almelo 1-3 PSV Eindhoven | Dutch Eredivisie |
| 3 | Sat 24 Aug | 327-1 v Almere CityAlmere City 1-7 PSV Eindhoven | Dutch Eredivisie |
| 4 | Sun 1 Sep | 323-0 v Go Ahead EaglesPSV Eindhoven 3-0 Go Ahead Eagles | Dutch Eredivisie |
| 5 | Sat 14 Sep | 322-0 v NEC NijmegenPSV Eindhoven 2-0 NEC Nijmegen | Dutch Eredivisie |
| 6 | Tue 17 Sep | 321-3 v JuventusJuventus 3-1 PSV Eindhoven | UEFA Champions League Matchday 1 |
| 7 | Sun 22 Sep | 323-1 v Fortuna SittardFortuna Sittard 1-3 PSV Eindhoven | Dutch Eredivisie |
| 8 | Sat 28 Sep | 32 2-0 v Willem IIWillem II 0-2 PSV Eindhoven | Dutch Eredivisie |
| 9 | Tue 1 Oct | 321-1 v Sporting CPPSV Eindhoven 1-1 Sporting CP | UEFA Champions League Matchday 2 |
| 10 | Sat 5 Oct | 32 2-1 v Sparta RotterdamPSV Eindhoven 2-1 Sparta Rotterdam | Dutch Eredivisie |
| 11 | Tue 22 Oct | 32 1-1 v Paris St GermainParis St Germain 1-1 PSV Eindhoven | UEFA Champions League Matchday 3 |
| 12 | Sat 26 Oct | 326-0 v PEC ZwollePSV Eindhoven 6-0 PEC Zwolle | Dutch Eredivisie |
| 13 | Sat 2 Nov | 322-3 v AjaxAjax 3-2 PSV Eindhoven | Dutch Eredivisie |
| 14 | Tue 5 Nov | 32 4-0 v GironaPSV Eindhoven 4-0 Girona | UEFA Champions League Matchday 4 |
| 15 | Sat 9 Nov | 323-0 v NAC BredaNAC Breda 0-3 PSV Eindhoven | Dutch Eredivisie |
| 16 | Sat 23 Nov | 325-0 v FC GroningenPSV Eindhoven 5-0 FC Groningen | Dutch Eredivisie |
| 17 | Wed 27 Nov | 323-2 v Shakhtar DonetskPSV Eindhoven 3-2 Shakhtar Donetsk | UEFA Champions League Matchday 5 |
| 18 | Sun 1 Dec | 325-2 v FC UtrechtFC Utrecht 2-5 PSV Eindhoven | Dutch Eredivisie |
| 19 | Fri 6 Dec | 326-1 v FC TwentePSV Eindhoven 6-1 FC Twente | Dutch Eredivisie |
| 20 | Tue 10 Dec | 32 0-1 v BrestBrest 1-0 PSV Eindhoven | UEFA Champions League Matchday 6 |
| 21 | Sun 22 Dec | 323-0 v FeyenoordPSV Eindhoven 3-0 Feyenoord | Dutch Eredivisie |
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