| 1 | Sun 18 Aug 2019 | 314-0 v 1. FC Union Berlin1. FC Union Berlin 0-4 RB Leipzig | German Bundesliga |
| 2 | Sun 25 Aug 2019 | 31 2-1 v Eintracht FrankfurtRB Leipzig 2-1 Eintracht Frankfurt | German Bundesliga |
| 3 | Fri 30 Aug 2019 | 313-1 v Borussia MönchengladbachBorussia Mönchengladbach 1-3 RB Leipzig | German Bundesliga |
| 4 | Sat 14 Sep 2019 | 311-1 v Bayern MunichRB Leipzig 1-1 Bayern Munich | German Bundesliga |
| 5 | Tue 17 Sep 2019 | 312-1 v BenficaBenfica 1-2 RB Leipzig | UEFA Champions League Group G |
| 6 | Sat 21 Sep 2019 | 313-0 v Werder BremenWerder Bremen 0-3 RB Leipzig | German Bundesliga |
| 7 | Sat 28 Sep 2019 | 311-3 v FC Schalke 04RB Leipzig 1-3 FC Schalke 04 | German Bundesliga |
| 8 | Sat 5 Oct 2019 | 31 1-1 v Bayer 04 LeverkusenBayer 04 Leverkusen 1-1 RB Leipzig | German Bundesliga |
| 9 | Sat 19 Oct 2019 | 311-1 v VfL WolfsburgRB Leipzig 1-1 VfL Wolfsburg | German Bundesliga |
| 10 | Wed 23 Oct 2019 | 312-1 v Zenit St PetersburgRB Leipzig 2-1 Zenit St Petersburg | UEFA Champions League Group G |
| 11 | Sat 26 Oct 2019 | 311-2 v SC FreiburgSC Freiburg 2-1 RB Leipzig | German Bundesliga |
| 12 | Sat 2 Nov 2019 | 318-0 v Mainz 05RB Leipzig 8-0 Mainz 05 | German Bundesliga |
| 13 | Tue 5 Nov 2019 | 312-0 v Zenit St PetersburgZenit St Petersburg 0-2 RB Leipzig | UEFA Champions League Group G |
| 14 | Sat 9 Nov 2019 | 314-2 v Hertha BerlinHertha Berlin 2-4 RB Leipzig | German Bundesliga |
| 15 | Sat 23 Nov 2019 | 314-1 v 1. FC KölnRB Leipzig 4-1 1. FC Köln | German Bundesliga |
| 16 | Wed 27 Nov 2019 | 312-2 v BenficaRB Leipzig 2-2 Benfica | UEFA Champions League Group G |
| 17 | Sat 30 Nov 2019 | 313-2 v SC Paderborn 07SC Paderborn 07 2-3 RB Leipzig | German Bundesliga |
| 18 | Sat 7 Dec 2019 | 313-1 v 1899 HoffenheimRB Leipzig 3-1 1899 Hoffenheim | German Bundesliga |
| 19 | Tue 10 Dec 2019 | 312-2 v LyonLyon 2-2 RB Leipzig | UEFA Champions League Group G |
| 20 | Sat 14 Dec 2019 | 31 3-0 v Fortuna DüsseldorfFortuna Düsseldorf 0-3 RB Leipzig | German Bundesliga |
| 21 | Tue 17 Dec 2019 | 313-3 v Borussia DortmundBorussia Dortmund 3-3 RB Leipzig | German Bundesliga |
| 22 | Sat 21 Dec 2019 | 313-1 v FC AugsburgRB Leipzig 3-1 FC Augsburg | German Bundesliga |
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