| 1 | Sat 19 Aug | 102-3 v Bayer 04 LeverkusenBayer 04 Leverkusen 3-2 RB Leipzig | German Bundesliga |
| 2 | Fri 25 Aug | 105-1 v VfB StuttgartRB Leipzig 5-1 VfB Stuttgart | German Bundesliga |
| 3 | Sun 3 Sep | 103-0 v 1 FC Union Berlin1 FC Union Berlin 0-3 RB Leipzig | German Bundesliga |
| 4 | Sat 16 Sep | 103-0 v FC AugsburgRB Leipzig 3-0 FC Augsburg | German Bundesliga |
| 5 | Tue 19 Sep | 10 3-1 v Young BoysYoung Boys 1-3 RB Leipzig | UEFA Champions League Group G |
| 6 | Sat 30 Sep | 102-2 v Bayern MunichRB Leipzig 2-2 Bayern Munich | German Bundesliga |
| 7 | Wed 4 Oct | 101-3 v Manchester CityRB Leipzig 1-3 Manchester City | UEFA Champions League Group G |
| 8 | Sat 7 Oct | 100-0 v VfL BochumRB Leipzig 0-0 VfL Bochum | German Bundesliga |
| 9 | Sat 21 Oct | 103-1 v Darmstadt 98Darmstadt 98 1-3 RB Leipzig | German Bundesliga |
| 10 | Wed 25 Oct | 103-1 v Red Star BelgradeRB Leipzig 3-1 Red Star Belgrade | UEFA Champions League Group G |
| 11 | Sat 4 Nov | 100-2 v Mainz 05Mainz 05 2-0 RB Leipzig | German Bundesliga |
| 12 | Tue 7 Nov | 102-1 v Red Star BelgradeRed Star Belgrade 1-2 RB Leipzig | UEFA Champions League Group G |
| 13 | Sun 12 Nov | 103-1 v SC FreiburgRB Leipzig 3-1 SC Freiburg | German Bundesliga |
| 14 | Sat 25 Nov | 101-2 v VfL WolfsburgVfL Wolfsburg 2-1 RB Leipzig | German Bundesliga |
| 15 | Tue 28 Nov | 102-3 v Manchester CityManchester City 3-2 RB Leipzig | UEFA Champions League Group G |
| 16 | Sat 2 Dec | 102-1 v 1 FC HeidenheimRB Leipzig 2-1 1 FC Heidenheim | German Bundesliga |
| 17 | Sat 9 Dec | 103-2 v Borussia DortmundBorussia Dortmund 2-3 RB Leipzig | German Bundesliga |
| 18 | Wed 13 Dec | 102-1 v Young BoysRB Leipzig 2-1 Young Boys | UEFA Champions League Group G |
| 19 | Sat 16 Dec | 103-1 v 1899 HoffenheimRB Leipzig 3-1 1899 Hoffenheim | German Bundesliga |
| 20 | Tue 19 Dec | 101-1 v Werder BremenWerder Bremen 1-1 RB Leipzig | German Bundesliga |
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