| 1 | Thu 15 Aug | 31-1 v GironaReal Betis 1-1 Girona | Spanish La Liga |
| 2 | Thu 22 Aug | 32-0 v Kryvbas KRKryvbas KR 0-2 Real Betis | UEFA Europa Conference League Play-off |
| 3 | Sun 25 Aug | 30-0 v AlavésAlavés 0-0 Real Betis | Spanish La Liga |
| 4 | Thu 29 Aug | 33-0 v Kryvbas KRReal Betis 3-0 Kryvbas KR | UEFA Europa Conference League Play-off |
| 5 | Sun 1 Sep | 30-2 v Real MadridReal Madrid 2-0 Real Betis | Spanish La Liga |
| 6 | Fri 13 Sep | 32-0 v LeganésReal Betis 2-0 Leganés | Spanish La Liga |
| 7 | Wed 18 Sep | 32-1 v GetafeReal Betis 2-1 Getafe | Spanish La Liga |
| 8 | Mon 23 Sep | 31-2 v MallorcaReal Betis 1-2 Mallorca | Spanish La Liga |
| 9 | Thu 26 Sep | 31-1 v Las PalmasLas Palmas 1-1 Real Betis | Spanish La Liga |
| 10 | Sun 29 Sep | 31-0 v EspanyolReal Betis 1-0 Espanyol | Spanish La Liga |
| 11 | Sun 6 Oct | 30-1 v SevillaSevilla 1-0 Real Betis | Spanish La Liga |
| 12 | Sat 19 Oct | 32-1 v OsasunaOsasuna 1-2 Real Betis | Spanish La Liga |
| 13 | Thu 24 Oct | 31-1 v FC CopenhagenReal Betis 1-1 FC Copenhagen | UEFA Europa Conference League Matchday 2 |
| 14 | Sun 27 Oct | 31-0 v Atlético MadridReal Betis 1-0 Atlético Madrid | Spanish La Liga |
| 15 | Sun 3 Nov | 31-1 v Athletic BilbaoAthletic Bilbao 1-1 Real Betis | Spanish La Liga |
| 16 | Thu 7 Nov | 32-1 v CeljeReal Betis 2-1 Celje | UEFA Europa Conference League Matchday 3 |
| 17 | Sun 10 Nov | 32-2 v Celta VigoReal Betis 2-2 Celta Vigo | Spanish La Liga |
| 18 | Thu 28 Nov | 3 1-2 v Mladá BoleslavMladá Boleslav 2-1 Real Betis | UEFA Europa Conference League Matchday 4 |
| 19 | Sun 1 Dec | 30-2 v Real SociedadReal Sociedad 2-0 Real Betis | Spanish La Liga |
| 20 | Sat 7 Dec | 32-2 v BarcelonaReal Betis 2-2 Barcelona | Spanish La Liga |
| 21 | Thu 12 Dec | 31-0 v Petrocub-HincestiPetrocub-Hincesti 0-1 Real Betis | UEFA Europa Conference League Matchday 5 |
| 22 | Sun 15 Dec | 32-1 v VillarrealVillarreal 1-2 Real Betis | Spanish La Liga |
| 23 | Thu 19 Dec | 31-0 v HJK HelsinkiReal Betis 1-0 HJK Helsinki | UEFA Europa Conference League Matchday 6 |
| 24 | Sun 22 Dec | 31-1 v Rayo VallecanoReal Betis 1-1 Rayo Vallecano | Spanish La Liga |
| 25 | Sat 11 Jan | 3 0-1 v Real ValladolidReal Valladolid 1-0 Real Betis | Spanish La Liga |
| 26 | Sat 18 Jan | 3 1-3 v AlavésReal Betis 1-3 Alavés | Spanish La Liga |
| 27 | Sat 25 Jan | 31-0 v MallorcaMallorca 0-1 Real Betis | Spanish La Liga |
| 28 | Sun 2 Feb | 32-2 v Athletic BilbaoReal Betis 2-2 Athletic Bilbao | Spanish La Liga |
| 29 | Sat 8 Feb | 3 2-3 v Celta VigoCelta Vigo 3-2 Real Betis | Spanish La Liga |
| 30 | Sun 16 Feb | 33-0 v Real SociedadReal Betis 3-0 Real Sociedad | Spanish La Liga |
| 31 | Thu 20 Feb | 30-1 v KAA GentReal Betis 0-1 KAA Gent | UEFA Europa Conference League Knockout Round |
| 32 | Sun 23 Feb | 32-1 v GetafeGetafe 1-2 Real Betis | Spanish La Liga |
| 33 | Sat 1 Mar | 32-1 v Real MadridReal Betis 2-1 Real Madrid | Spanish La Liga |
| 34 | Sun 9 Mar | 3 1-0 v Las PalmasReal Betis 1-0 Las Palmas | Spanish La Liga |
| 35 | Thu 13 Mar | 3 4-0 v Vitória GuimarãesVitória Guimarães 0-4 Real Betis | UEFA Europa Conference League Round of 16 |
| 36 | Sun 16 Mar | 33-2 v LeganésLeganés 2-3 Real Betis | Spanish La Liga |
| 37 | Sun 30 Mar | 32-1 v SevillaReal Betis 2-1 Sevilla | Spanish La Liga |
| 38 | Sat 5 Apr | 31-1 v BarcelonaBarcelona 1-1 Real Betis | Spanish La Liga |
| 39 | Thu 10 Apr | 32-0 v Jagiellonia BiałystokReal Betis 2-0 Jagiellonia Białystok | UEFA Europa Conference League Quarter Final |
| 40 | Sun 13 Apr | 31-2 v VillarrealReal Betis 1-2 Villarreal | Spanish La Liga |
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