| 1 | Sun 13 Aug | 5 2-1 v VillarrealVillarreal 1-2 Real Betis | Spanish La Liga |
| 2 | Sun 20 Aug | 50-0 v Atlético MadridReal Betis 0-0 Atlético Madrid | Spanish La Liga |
| 3 | Sun 27 Aug | 5 2-4 v Athletic BilbaoAthletic Bilbao 4-2 Real Betis | Spanish La Liga |
| 4 | Sat 2 Sep | 5 1-0 v Rayo VallecanoReal Betis 1-0 Rayo Vallecano | Spanish La Liga |
| 5 | Sat 16 Sep | 5 0-5 v BarcelonaBarcelona 5-0 Real Betis | Spanish La Liga |
| 6 | Thu 21 Sep | 50-1 v RangersRangers 1-0 Real Betis | UEFA Europa League Group C |
| 7 | Sun 24 Sep | 51-1 v CádizReal Betis 1-1 Cádiz | Spanish La Liga |
| 8 | Thu 28 Sep | 51-1 v GranadaGranada 1-1 Real Betis | Spanish La Liga |
| 9 | Sun 1 Oct | 53-0 v ValenciaReal Betis 3-0 Valencia | Spanish La Liga |
| 10 | Thu 5 Oct | 5 2-1 v Sparta PragueReal Betis 2-1 Sparta Prague | UEFA Europa League Group C |
| 11 | Sun 8 Oct | 5 1-1 v AlavésAlavés 1-1 Real Betis | Spanish La Liga |
| 12 | Thu 26 Oct | 51-0 v Aris LimassolAris Limassol 0-1 Real Betis | UEFA Europa League Group C |
| 13 | Sun 29 Oct | 52-1 v OsasunaReal Betis 2-1 Osasuna | Spanish La Liga |
| 14 | Sat 4 Nov | 52-0 v MallorcaReal Betis 2-0 Mallorca | Spanish La Liga |
| 15 | Thu 9 Nov | 5 4-1 v Aris LimassolReal Betis 4-1 Aris Limassol | UEFA Europa League Group C |
| 16 | Sun 12 Nov | 51-1 v SevillaSevilla 1-1 Real Betis | Spanish La Liga |
| 17 | Sun 26 Nov | 51-0 v Las PalmasReal Betis 1-0 Las Palmas | Spanish La Liga |
| 18 | Thu 30 Nov | 5 0-1 v Sparta PragueSparta Prague 1-0 Real Betis | UEFA Europa League Group C |
| 19 | Sun 3 Dec | 50-0 v AlmeríaAlmería 0-0 Real Betis | Spanish La Liga |
| 20 | Sun 3 Mar | 5 1-2 v Atlético MadridAtlético Madrid 2-1 Real Betis | Spanish La Liga |
| 21 | Sun 10 Mar | 52-3 v VillarrealReal Betis 2-3 Villarreal | Spanish La Liga |
| 22 | Sun 17 Mar | 50-2 v Rayo VallecanoRayo Vallecano 2-0 Real Betis | Spanish La Liga |
| 23 | Sun 31 Mar | 52-3 v GironaGirona 3-2 Real Betis | Spanish La Liga |
| 24 | Fri 12 Apr | 52-1 v Celta VigoReal Betis 2-1 Celta Vigo | Spanish La Liga |
| 25 | Sat 20 Apr | 52-1 v ValenciaValencia 1-2 Real Betis | Spanish La Liga |
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