| 1 | Sat 2 Sep | 21-0 v Rayo VallecanoReal Betis 1-0 Rayo Vallecano | Spanish La Liga |
| 2 | Sat 16 Sep | 20-5 v BarcelonaBarcelona 5-0 Real Betis | Spanish La Liga |
| 3 | Thu 21 Sep | 20-1 v RangersRangers 1-0 Real Betis | UEFA Europa League Group C |
| 4 | Sun 24 Sep | 21-1 v CádizReal Betis 1-1 Cádiz | Spanish La Liga |
| 5 | Sun 1 Oct | 23-0 v ValenciaReal Betis 3-0 Valencia | Spanish La Liga |
| 6 | Thu 5 Oct | 22-1 v Sparta PragueReal Betis 2-1 Sparta Prague | UEFA Europa League Group C |
| 7 | Sun 8 Oct | 21-1 v AlavésAlavés 1-1 Real Betis | Spanish La Liga |
| 8 | Sat 21 Oct | 21-1 v GetafeGetafe 1-1 Real Betis | Spanish La Liga |
| 9 | Sun 29 Oct | 22-1 v OsasunaReal Betis 2-1 Osasuna | Spanish La Liga |
| 10 | Sat 4 Nov | 22-0 v MallorcaReal Betis 2-0 Mallorca | Spanish La Liga |
| 11 | Sun 12 Nov | 21-1 v SevillaSevilla 1-1 Real Betis | Spanish La Liga |
| 12 | Sun 26 Nov | 21-0 v Las PalmasReal Betis 1-0 Las Palmas | Spanish La Liga |
| 13 | Sun 3 Dec | 2 0-0 v AlmeríaAlmería 0-0 Real Betis | Spanish La Liga |
| 14 | Thu 14 Dec | 22-3 v RangersReal Betis 2-3 Rangers | UEFA Europa League Group C |
| 15 | Thu 21 Dec | 21-1 v GironaReal Betis 1-1 Girona | Spanish La Liga |
| 16 | Sun 21 Jan | 22-4 v BarcelonaReal Betis 2-4 Barcelona | Spanish La Liga |
| 17 | Sat 27 Jan | 21-0 v MallorcaMallorca 0-1 Real Betis | Spanish La Liga |
| 18 | Sun 4 Feb | 21-1 v GetafeReal Betis 1-1 Getafe | Spanish La Liga |
| 19 | Fri 9 Feb | 22-0 v CádizCádiz 0-2 Real Betis | Spanish La Liga |
| 20 | Thu 15 Feb | 20-1 v Dinamo ZagrebReal Betis 0-1 Dinamo Zagreb | UEFA Europa Conference League |
| 21 | Sun 18 Feb | 20-0 v AlavésReal Betis 0-0 Alavés | Spanish La Liga |
| 22 | Thu 22 Feb | 21-1 v Dinamo ZagrebDinamo Zagreb 1-1 Real Betis | UEFA Europa Conference League |
| 23 | Sun 25 Feb | 23-1 v Athletic BilbaoReal Betis 3-1 Athletic Bilbao | Spanish La Liga |
| 24 | Sun 3 Mar | 21-2 v Atlético MadridAtlético Madrid 2-1 Real Betis | Spanish La Liga |
| 25 | Fri 12 Apr | 22-1 v Celta VigoReal Betis 2-1 Celta Vigo | Spanish La Liga |
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