| 1 | Thu 15 Aug | 51-1 v GironaReal Betis 1-1 Girona | Spanish La Liga |
| 2 | Sun 25 Aug | 50-0 v AlavésAlavés 0-0 Real Betis | Spanish La Liga |
| 3 | Sat 19 Oct | 52-1 v OsasunaOsasuna 1-2 Real Betis | Spanish La Liga |
| 4 | Sun 27 Oct | 51-0 v Atlético MadridReal Betis 1-0 Atlético Madrid | Spanish La Liga |
| 5 | Sun 3 Nov | 51-1 v Athletic BilbaoAthletic Bilbao 1-1 Real Betis | Spanish La Liga |
| 6 | Thu 7 Nov | 52-1 v CeljeReal Betis 2-1 Celje | UEFA Europa Conference League Matchday 3 |
| 7 | Sun 10 Nov | 52-2 v Celta VigoReal Betis 2-2 Celta Vigo | Spanish La Liga |
| 8 | Sat 23 Nov | 52-4 v ValenciaValencia 4-2 Real Betis | Spanish La Liga |
| 9 | Sun 1 Dec | 5 0-2 v Real SociedadReal Sociedad 2-0 Real Betis | Spanish La Liga |
| 10 | Sat 7 Dec | 52-2 v BarcelonaReal Betis 2-2 Barcelona | Spanish La Liga |
| 11 | Sun 15 Dec | 52-1 v VillarrealVillarreal 1-2 Real Betis | Spanish La Liga |
| 12 | Sun 22 Dec | 51-1 v Rayo VallecanoReal Betis 1-1 Rayo Vallecano | Spanish La Liga |
| 13 | Sat 18 Jan | 51-3 v AlavésReal Betis 1-3 Alavés | Spanish La Liga |
| 14 | Thu 13 Feb | 53-0 v KAA GentKAA Gent 0-3 Real Betis | UEFA Europa Conference League Knockout Round |
| 15 | Sun 16 Feb | 53-0 v Real SociedadReal Betis 3-0 Real Sociedad | Spanish La Liga |
| 16 | Thu 20 Feb | 50-1 v KAA GentReal Betis 0-1 KAA Gent | UEFA Europa Conference League Knockout Round |
| 17 | Sun 23 Feb | 52-1 v GetafeGetafe 1-2 Real Betis | Spanish La Liga |
| 18 | Sat 1 Mar | 52-1 v Real MadridReal Betis 2-1 Real Madrid | Spanish La Liga |
| 19 | Thu 6 Mar | 52-2 v Vitória GuimarãesReal Betis 2-2 Vitória Guimarães | UEFA Europa Conference League Round of 16 |
| 20 | Thu 13 Mar | 54-0 v Vitória GuimarãesVitória Guimarães 0-4 Real Betis | UEFA Europa Conference League Round of 16 |
| 21 | Sun 16 Mar | 53-2 v LeganésLeganés 2-3 Real Betis | Spanish La Liga |
| 22 | Sun 30 Mar | 52-1 v SevillaReal Betis 2-1 Sevilla | Spanish La Liga |
| 23 | Sat 5 Apr | 51-1 v BarcelonaBarcelona 1-1 Real Betis | Spanish La Liga |
| 24 | Thu 10 Apr | 52-0 v Jagiellonia BiałystokReal Betis 2-0 Jagiellonia Białystok | UEFA Europa Conference League Quarter Final |
| 25 | Sun 13 Apr | 51-2 v VillarrealReal Betis 1-2 Villarreal | Spanish La Liga |
| 26 | Thu 17 Apr | 51-1 v Jagiellonia BiałystokJagiellonia Białystok 1-1 Real Betis | UEFA Europa Conference League Quarter Final |
| 27 | Mon 21 Apr | 53-1 v GironaGirona 1-3 Real Betis | Spanish La Liga |
| 28 | Thu 24 Apr | 55-1 v Real ValladolidReal Betis 5-1 Real Valladolid | Spanish La Liga |
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