| 1 | Sat 4 Nov | 82-0 v MallorcaReal Betis 2-0 Mallorca | Spanish La Liga |
| 2 | Thu 9 Nov | 84-1 v Aris LimassolReal Betis 4-1 Aris Limassol | UEFA Europa League Group C |
| 3 | Sun 26 Nov | 81-0 v Las PalmasReal Betis 1-0 Las Palmas | Spanish La Liga |
| 4 | Thu 30 Nov | 80-1 v Sparta PragueSparta Prague 1-0 Real Betis | UEFA Europa League Group C |
| 5 | Sat 13 Jan | 81-0 v GranadaReal Betis 1-0 Granada | Spanish La Liga |
| 6 | Sun 21 Jan | 82-4 v BarcelonaReal Betis 2-4 Barcelona | Spanish La Liga |
| 7 | Sat 27 Jan | 81-0 v MallorcaMallorca 0-1 Real Betis | Spanish La Liga |
| 8 | Sun 4 Feb | 81-1 v GetafeReal Betis 1-1 Getafe | Spanish La Liga |
| 9 | Fri 9 Feb | 82-0 v CádizCádiz 0-2 Real Betis | Spanish La Liga |
| 10 | Thu 15 Feb | 80-1 v Dinamo ZagrebReal Betis 0-1 Dinamo Zagreb | UEFA Europa Conference League |
| 11 | Sun 18 Feb | 80-0 v AlavésReal Betis 0-0 Alavés | Spanish La Liga |
| 12 | Thu 22 Feb | 81-1 v Dinamo ZagrebDinamo Zagreb 1-1 Real Betis | UEFA Europa Conference League |
| 13 | Sun 25 Feb | 83-1 v Athletic BilbaoReal Betis 3-1 Athletic Bilbao | Spanish La Liga |
| 14 | Sun 10 Mar | 82-3 v VillarrealReal Betis 2-3 Villarreal | Spanish La Liga |
| 15 | Sun 17 Mar | 80-2 v Rayo VallecanoRayo Vallecano 2-0 Real Betis | Spanish La Liga |
| 16 | Sun 31 Mar | 82-3 v GironaGirona 3-2 Real Betis | Spanish La Liga |
| 17 | Fri 12 Apr | 82-1 v Celta VigoReal Betis 2-1 Celta Vigo | Spanish La Liga |
| 18 | Sat 20 Apr | 82-1 v ValenciaValencia 1-2 Real Betis | Spanish La Liga |
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