| 1 | Sun 13 Aug | 132-1 v VillarrealVillarreal 1-2 Real Betis | Spanish La Liga |
| 2 | Sun 20 Aug | 130-0 v Atlético MadridReal Betis 0-0 Atlético Madrid | Spanish La Liga |
| 3 | Sun 27 Aug | 132-4 v Athletic BilbaoAthletic Bilbao 4-2 Real Betis | Spanish La Liga |
| 4 | Sat 2 Sep | 131-0 v Rayo VallecanoReal Betis 1-0 Rayo Vallecano | Spanish La Liga |
| 5 | Sat 16 Sep | 130-5 v BarcelonaBarcelona 5-0 Real Betis | Spanish La Liga |
| 6 | Thu 5 Oct | 132-1 v Sparta PragueReal Betis 2-1 Sparta Prague | UEFA Europa League Group C |
| 7 | Thu 26 Oct | 131-0 v Aris LimassolAris Limassol 0-1 Real Betis | UEFA Europa League Group C |
| 8 | Thu 30 Nov | 130-1 v Sparta PragueSparta Prague 1-0 Real Betis | UEFA Europa League Group C |
| 9 | Sun 3 Dec | 13 0-0 v AlmeríaAlmería 0-0 Real Betis | Spanish La Liga |
| 10 | Sat 9 Dec | 131-1 v Real MadridReal Betis 1-1 Real Madrid | Spanish La Liga |
| 11 | Thu 14 Dec | 132-3 v RangersReal Betis 2-3 Rangers | UEFA Europa League Group C |
| 12 | Sun 17 Dec | 130-0 v Real SociedadReal Sociedad 0-0 Real Betis | Spanish La Liga |
| 13 | Thu 21 Dec | 131-1 v GironaReal Betis 1-1 Girona | Spanish La Liga |
| 14 | Wed 3 Jan | 131-2 v Celta VigoCelta Vigo 2-1 Real Betis | Spanish La Liga |
| 15 | Sat 13 Jan | 131-0 v GranadaReal Betis 1-0 Granada | Spanish La Liga |
| 16 | Sun 21 Jan | 132-4 v BarcelonaReal Betis 2-4 Barcelona | Spanish La Liga |
| 17 | Sat 27 Jan | 13 1-0 v MallorcaMallorca 0-1 Real Betis | Spanish La Liga |
| 18 | Sun 4 Feb | 13 1-1 v GetafeReal Betis 1-1 Getafe | Spanish La Liga |
| 19 | Fri 9 Feb | 132-0 v CádizCádiz 0-2 Real Betis | Spanish La Liga |
| 20 | Thu 15 Feb | 130-1 v Dinamo ZagrebReal Betis 0-1 Dinamo Zagreb | UEFA Europa Conference League |
| 21 | Sun 18 Feb | 130-0 v AlavésReal Betis 0-0 Alavés | Spanish La Liga |
| 22 | Thu 22 Feb | 131-1 v Dinamo ZagrebDinamo Zagreb 1-1 Real Betis | UEFA Europa Conference League |
| 23 | Sun 25 Feb | 133-1 v Athletic BilbaoReal Betis 3-1 Athletic Bilbao | Spanish La Liga |
| 24 | Sun 3 Mar | 131-2 v Atlético MadridAtlético Madrid 2-1 Real Betis | Spanish La Liga |
| 25 | Sun 10 Mar | 132-3 v VillarrealReal Betis 2-3 Villarreal | Spanish La Liga |
| 26 | Sun 17 Mar | 130-2 v Rayo VallecanoRayo Vallecano 2-0 Real Betis | Spanish La Liga |
| 27 | Sun 31 Mar | 132-3 v GironaGirona 3-2 Real Betis | Spanish La Liga |
| 28 | Fri 12 Apr | 132-1 v Celta VigoReal Betis 2-1 Celta Vigo | Spanish La Liga |
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