| 1 | Sun 1 Sep | 80-2 v Real MadridReal Madrid 2-0 Real Betis | Spanish La Liga |
| 2 | Fri 13 Sep | 82-0 v LeganésReal Betis 2-0 Leganés | Spanish La Liga |
| 3 | Wed 18 Sep | 82-1 v GetafeReal Betis 2-1 Getafe | Spanish La Liga |
| 4 | Mon 23 Sep | 81-2 v MallorcaReal Betis 1-2 Mallorca | Spanish La Liga |
| 5 | Sun 29 Sep | 81-0 v EspanyolReal Betis 1-0 Espanyol | Spanish La Liga |
| 6 | Thu 3 Oct | 80-1 v Legia WarsawLegia Warsaw 1-0 Real Betis | UEFA Europa Conference League Matchday 1 |
| 7 | Sun 6 Oct | 80-1 v SevillaSevilla 1-0 Real Betis | Spanish La Liga |
| 8 | Sat 19 Oct | 82-1 v OsasunaOsasuna 1-2 Real Betis | Spanish La Liga |
| 9 | Thu 24 Oct | 81-1 v FC CopenhagenReal Betis 1-1 FC Copenhagen | UEFA Europa Conference League Matchday 2 |
| 10 | Sun 27 Oct | 81-0 v Atlético MadridReal Betis 1-0 Atlético Madrid | Spanish La Liga |
| 11 | Sun 3 Nov | 81-1 v Athletic BilbaoAthletic Bilbao 1-1 Real Betis | Spanish La Liga |
| 12 | Thu 7 Nov | 82-1 v CeljeReal Betis 2-1 Celje | UEFA Europa Conference League Matchday 3 |
| 13 | Sun 10 Nov | 82-2 v Celta VigoReal Betis 2-2 Celta Vigo | Spanish La Liga |
| 14 | Sat 23 Nov | 82-4 v ValenciaValencia 4-2 Real Betis | Spanish La Liga |
| 15 | Thu 28 Nov | 81-2 v Mladá BoleslavMladá Boleslav 2-1 Real Betis | UEFA Europa Conference League Matchday 4 |
| 16 | Sun 1 Dec | 80-2 v Real SociedadReal Sociedad 2-0 Real Betis | Spanish La Liga |
| 17 | Sat 7 Dec | 82-2 v BarcelonaReal Betis 2-2 Barcelona | Spanish La Liga |
| 18 | Thu 12 Dec | 81-0 v Petrocub-HincestiPetrocub-Hincesti 0-1 Real Betis | UEFA Europa Conference League Matchday 5 |
| 19 | Sun 15 Dec | 8 2-1 v VillarrealVillarreal 1-2 Real Betis | Spanish La Liga |
| 20 | Thu 19 Dec | 81-0 v HJK HelsinkiReal Betis 1-0 HJK Helsinki | UEFA Europa Conference League Matchday 6 |
| 21 | Sun 22 Dec | 81-1 v Rayo VallecanoReal Betis 1-1 Rayo Vallecano | Spanish La Liga |
| 22 | Sat 11 Jan | 8 0-1 v Real ValladolidReal Valladolid 1-0 Real Betis | Spanish La Liga |
| 23 | Sat 18 Jan | 8 1-3 v AlavésReal Betis 1-3 Alavés | Spanish La Liga |
| 24 | Sat 25 Jan | 81-0 v MallorcaMallorca 0-1 Real Betis | Spanish La Liga |
| 25 | Sun 2 Feb | 82-2 v Athletic BilbaoReal Betis 2-2 Athletic Bilbao | Spanish La Liga |
| 26 | Sat 8 Feb | 8 2-3 v Celta VigoCelta Vigo 3-2 Real Betis | Spanish La Liga |
| 27 | Sun 16 Feb | 83-0 v Real SociedadReal Betis 3-0 Real Sociedad | Spanish La Liga |
| 28 | Thu 20 Feb | 8 0-1 v KAA GentReal Betis 0-1 KAA Gent | UEFA Europa Conference League Knockout Round |
| 29 | Sun 23 Feb | 82-1 v GetafeGetafe 1-2 Real Betis | Spanish La Liga |
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