| 1 | Sun 15 Aug 2021 | 63-0 v Rayo VallecanoSevilla 3-0 Rayo Vallecano | Spanish La Liga |
| 2 | Wed 22 Sep 2021 | 6 3-1 v ValenciaSevilla 3-1 Valencia | Spanish La Liga |
| 3 | Sun 17 Oct 2021 | 61-0 v Celta VigoCelta Vigo 0-1 Sevilla | Spanish La Liga |
| 4 | Sat 30 Oct 2021 | 62-0 v OsasunaSevilla 2-0 Osasuna | Spanish La Liga |
| 5 | Sat 11 Dec 2021 | 61-0 v Athletic BilbaoAthletic Bilbao 0-1 Sevilla | Spanish La Liga |
| 6 | Sat 18 Dec 2021 | 62-1 v Atlético MadridSevilla 2-1 Atlético Madrid | Spanish La Liga |
| 7 | Tue 21 Dec 2021 | 61-1 v BarcelonaSevilla 1-1 Barcelona | Spanish La Liga |
| 8 | Mon 3 Jan 2022 | 61-0 v CádizCádiz 0-1 Sevilla | Spanish La Liga |
| 9 | Sun 9 Jan 2022 | 61-0 v GetafeSevilla 1-0 Getafe | Spanish La Liga |
| 10 | Sat 22 Jan 2022 | 6 2-2 v Celta VigoSevilla 2-2 Celta Vigo | Spanish La Liga |
| 11 | Sat 5 Feb 2022 | 6 0-0 v OsasunaOsasuna 0-0 Sevilla | Spanish La Liga |
| 12 | Thu 17 Feb 2022 | 63-1 v Dinamo ZagrebSevilla 3-1 Dinamo Zagreb | UEFA Europa League Round of 32 |
| 13 | Sun 27 Feb 2022 | 62-1 v Real BetisSevilla 2-1 Real Betis | Spanish La Liga |
| 14 | Fri 4 Mar 2022 | 60-0 v AlavésAlavés 0-0 Sevilla | Spanish La Liga |
| 15 | Thu 10 Mar 2022 | 61-0 v West Ham UnitedSevilla 1-0 West Ham United | UEFA Europa League Round of 16 |
| 16 | Sun 13 Mar 2022 | 61-1 v Rayo VallecanoRayo Vallecano 1-1 Sevilla | Spanish La Liga |
| 17 | Thu 17 Mar 2022 | 60-2 v West Ham UnitedWest Ham United 2-0 Sevilla | UEFA Europa League Round of 16 |
| 18 | Sun 20 Mar 2022 | 60-0 v Real SociedadSevilla 0-0 Real Sociedad | Spanish La Liga |
| 19 | Sun 3 Apr 2022 | 60-1 v BarcelonaBarcelona 1-0 Sevilla | Spanish La Liga |
| 20 | Fri 8 Apr 2022 | 64-2 v GranadaSevilla 4-2 Granada | Spanish La Liga |
| 21 | Sun 17 Apr 2022 | 62-3 v Real MadridSevilla 2-3 Real Madrid | Spanish La Liga |
| 22 | Sun 8 May 2022 | 61-1 v VillarrealVillarreal 1-1 Sevilla | Spanish La Liga |
| 23 | Wed 11 May 2022 | 6 0-0 v MallorcaSevilla 0-0 Mallorca | Spanish La Liga |
| 24 | Sun 15 May 2022 | 6 1-1 v Atlético MadridAtlético Madrid 1-1 Sevilla | Spanish La Liga |
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