| 1 | Sat 14 Aug 2021 | 60-0 v Swansea CitySwansea City 0-0 Sheffield United | Sky Bet Championship |
| 2 | Wed 18 Aug 2021 | 60-4 v West Bromwich AlbionWest Bromwich Albion 4-0 Sheffield United | Sky Bet Championship |
| 3 | Sat 21 Aug 2021 | 61-2 v Huddersfield TownSheffield United 1-2 Huddersfield Town | Sky Bet Championship |
| 4 | Sat 28 Aug 2021 | 60-0 v Luton TownLuton Town 0-0 Sheffield United | Sky Bet Championship |
| 5 | Sat 18 Sep 2021 | 63-1 v Hull CityHull City 1-3 Sheffield United | Sky Bet Championship |
| 6 | Tue 21 Sep 2021 | 62-2 v SouthamptonSheffield United 2-2 Southampton | Carabao Cup Third Round |
| 7 | Sat 2 Oct 2021 | 61-2 v AFC BournemouthAFC Bournemouth 2-1 Sheffield United | Sky Bet Championship |
| 8 | Sun 24 Oct 2021 | 63-2 v BarnsleyBarnsley 2-3 Sheffield United | Sky Bet Championship |
| 9 | Tue 2 Nov 2021 | 61-1 v Nottingham ForestNottingham Forest 1-1 Sheffield United | Sky Bet Championship |
| 10 | Sat 6 Nov 2021 | 61-3 v Blackburn RoversBlackburn Rovers 3-1 Sheffield United | Sky Bet Championship |
| 11 | Sat 20 Nov 2021 | 60-0 v Coventry CitySheffield United 0-0 Coventry City | Sky Bet Championship |
| 12 | Tue 23 Nov 2021 | 61-0 v ReadingReading 0-1 Sheffield United | Sky Bet Championship |
| 13 | Sun 28 Nov 2021 | 62-0 v Bristol CitySheffield United 2-0 Bristol City | Sky Bet Championship |
| 14 | Sat 4 Dec 2021 | 63-2 v Cardiff CityCardiff City 2-3 Sheffield United | Sky Bet Championship |
| 15 | Mon 20 Dec 2021 | 61-0 v FulhamFulham 0-1 Sheffield United | Sky Bet Championship |
| 16 | Sun 9 Jan 2022 | 6 0-3 v Wolverhampton WanderersWolverhampton Wanderers 3-0 Sheffield United | Emirates FA Cup Third Round |
| 17 | Sat 15 Jan 2022 | 60-2 v Derby CountyDerby County 2-0 Sheffield United | Sky Bet Championship |
| 18 | Tue 18 Jan 2022 | 62-2 v Preston North EndPreston North End 2-2 Sheffield United | Sky Bet Championship |
| 19 | Sat 22 Jan 2022 | 62-0 v Luton TownSheffield United 2-0 Luton Town | Sky Bet Championship |
| 20 | Sat 29 Jan 2022 | 62-0 v Peterborough UnitedPeterborough United 0-2 Sheffield United | Sky Bet Championship |
| 21 | Fri 4 Feb 2022 | 62-1 v Birmingham CityBirmingham City 1-2 Sheffield United | Sky Bet Championship |
| 22 | Wed 9 Feb 2022 | 62-0 v West Bromwich AlbionSheffield United 2-0 West Bromwich Albion | Sky Bet Championship |
| 23 | Sat 12 Feb 2022 | 60-0 v Huddersfield TownHuddersfield Town 0-0 Sheffield United | Sky Bet Championship |
| 24 | Tue 15 Feb 2022 | 60-0 v Hull CitySheffield United 0-0 Hull City | Sky Bet Championship |
| 25 | Sat 19 Feb 2022 | 64-0 v Swansea CitySheffield United 4-0 Swansea City | Sky Bet Championship |
| 26 | Mon 18 Apr 2022 | 6 1-1 v Bristol CityBristol City 1-1 Sheffield United | Sky Bet Championship |
| 27 | Sat 23 Apr 2022 | 61-0 v Cardiff CitySheffield United 1-0 Cardiff City | Sky Bet Championship |
| 28 | Fri 29 Apr 2022 | 63-1 v Queens Park RangersQueens Park Rangers 1-3 Sheffield United | Sky Bet Championship |
| 29 | Sat 7 May 2022 | 64-0 v FulhamSheffield United 4-0 Fulham | Sky Bet Championship |
| 30 | Sat 14 May 2022 | 61-2 v Nottingham ForestSheffield United 1-2 Nottingham Forest | Sky Bet Championship Play-off Semi Final |
| 31 | Tue 17 May 2022 | 62-1 v Nottingham ForestNottingham Forest 1-2 Sheffield United | Sky Bet Championship Play-off Semi Final |
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