| 1 | Fri 4 Aug | 9 2-1 v Sheffield WednesdaySheffield Wednesday 1-2 Southampton | Sky Bet Championship |
| 2 | Sat 12 Aug | 94-4 v Norwich CitySouthampton 4-4 Norwich City | Sky Bet Championship |
| 3 | Sat 19 Aug | 92-1 v Plymouth ArgylePlymouth Argyle 1-2 Southampton | Sky Bet Championship |
| 4 | Sat 26 Aug | 92-1 v Queens Park RangersSouthampton 2-1 Queens Park Rangers | Sky Bet Championship |
| 5 | Sat 2 Sep | 90-5 v SunderlandSunderland 5-0 Southampton | Sky Bet Championship |
| 6 | Fri 15 Sep | 91-4 v Leicester CitySouthampton 1-4 Leicester City | Sky Bet Championship |
| 7 | Tue 19 Sep | 90-1 v Ipswich TownSouthampton 0-1 Ipswich Town | Sky Bet Championship |
| 8 | Sat 23 Sep | 91-2 v MiddlesbroughMiddlesbrough 2-1 Southampton | Sky Bet Championship |
| 9 | Sat 30 Sep | 9 3-1 v Leeds UnitedSouthampton 3-1 Leeds United | Sky Bet Championship |
| 10 | Tue 3 Oct | 91-0 v Stoke CityStoke City 0-1 Southampton | Sky Bet Championship |
| 11 | Sat 7 Oct | 91-1 v Rotherham UnitedSouthampton 1-1 Rotherham United | Sky Bet Championship |
| 12 | Sat 21 Oct | 92-1 v Hull CityHull City 1-2 Southampton | Sky Bet Championship |
| 13 | Wed 25 Oct | 92-2 v Preston North EndPreston North End 2-2 Southampton | Sky Bet Championship |
| 14 | Sat 28 Oct | 93-1 v Birmingham CitySouthampton 3-1 Birmingham City | Sky Bet Championship |
| 15 | Sat 4 Nov | 91-0 v MillwallMillwall 0-1 Southampton | Sky Bet Championship |
| 16 | Sat 11 Nov | 92-1 v West Bromwich AlbionSouthampton 2-1 West Bromwich Albion | Sky Bet Championship |
| 17 | Sat 25 Nov | 91-1 v Huddersfield TownHuddersfield Town 1-1 Southampton | Sky Bet Championship |
| 18 | Wed 29 Nov | 9 1-0 v Bristol CitySouthampton 1-0 Bristol City | Sky Bet Championship |
| 19 | Sat 2 Dec | 92-0 v Cardiff CitySouthampton 2-0 Cardiff City | Sky Bet Championship |
| 20 | Sat 9 Dec | 9 1-1 v WatfordWatford 1-1 Southampton | Sky Bet Championship |
| 21 | Wed 13 Dec | 91-1 v Coventry CityCoventry City 1-1 Southampton | Sky Bet Championship |
| 22 | Sat 16 Dec | 94-0 v Blackburn RoversSouthampton 4-0 Blackburn Rovers | Sky Bet Championship |
| 23 | Sat 23 Dec | 91-0 v Queens Park RangersQueens Park Rangers 0-1 Southampton | Sky Bet Championship |
| 24 | Tue 26 Dec | 95-0 v Swansea CitySouthampton 5-0 Swansea City | Sky Bet Championship |
| 25 | Fri 29 Dec | 92-1 v Plymouth ArgyleSouthampton 2-1 Plymouth Argyle | Sky Bet Championship |
| 26 | Mon 1 Jan | 91-1 v Norwich CityNorwich City 1-1 Southampton | Sky Bet Championship |
| 27 | Sat 13 Jan | 9 4-0 v Sheffield WednesdaySouthampton 4-0 Sheffield Wednesday | Sky Bet Championship |
| 28 | Sat 20 Jan | 93-1 v Swansea CitySwansea City 1-3 Southampton | Sky Bet Championship |
| 29 | Sun 28 Jan | 91-1 v WatfordWatford 1-1 Southampton | Emirates FA Cup Fourth Round |
| 30 | Sat 3 Feb | 92-0 v Rotherham UnitedRotherham United 0-2 Southampton | Sky Bet Championship |
| 31 | Tue 6 Feb | 9 3-0 v WatfordSouthampton 3-0 Watford | Emirates FA Cup Fourth Round Replay |
| 32 | Sat 10 Feb | 95-3 v Huddersfield TownSouthampton 5-3 Huddersfield Town | Sky Bet Championship |
| 33 | Tue 13 Feb | 91-3 v Bristol CityBristol City 3-1 Southampton | Sky Bet Championship |
| 34 | Fri 16 Feb | 92-0 v West Bromwich AlbionWest Bromwich Albion 0-2 Southampton | Sky Bet Championship |
| 35 | Tue 20 Feb | 91-2 v Hull CitySouthampton 1-2 Hull City | Sky Bet Championship |
| 36 | Sat 24 Feb | 91-2 v MillwallSouthampton 1-2 Millwall | Sky Bet Championship |
| 37 | Wed 28 Feb | 90-3 v LiverpoolLiverpool 3-0 Southampton | Emirates FA Cup Fifth Round |
| 38 | Sat 2 Mar | 94-3 v Birmingham CityBirmingham City 3-4 Southampton | Sky Bet Championship |
| 39 | Sat 9 Mar | 94-2 v SunderlandSouthampton 4-2 Sunderland | Sky Bet Championship |
| 40 | Fri 29 Mar | 91-1 v MiddlesbroughSouthampton 1-1 Middlesbrough | Sky Bet Championship |
| 41 | Mon 1 Apr | 92-3 v Ipswich TownIpswich Town 3-2 Southampton | Sky Bet Championship |
| 42 | Sat 6 Apr | 90-0 v Blackburn RoversBlackburn Rovers 0-0 Southampton | Sky Bet Championship |
| 43 | Tue 9 Apr | 92-1 v Coventry CitySouthampton 2-1 Coventry City | Sky Bet Championship |
| 44 | Sat 13 Apr | 93-2 v WatfordSouthampton 3-2 Watford | Sky Bet Championship |
| 45 | Tue 16 Apr | 93-0 v Preston North EndSouthampton 3-0 Preston North End | Sky Bet Championship |
| 46 | Sat 20 Apr | 91-2 v Cardiff CityCardiff City 2-1 Southampton | Sky Bet Championship |
| 47 | Tue 23 Apr | 90-5 v Leicester CityLeicester City 5-0 Southampton | Sky Bet Championship |
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