| 1 | Sat 6 Feb 2021 | 243-0 v GetafeSevilla 3-0 Getafe |
| 2 | Sat 13 Feb 2021 | 241-0 v HuescaSevilla 1-0 Huesca |
| 3 | Mon 22 Feb 2021 | 242-0 v OsasunaOsasuna 0-2 Sevilla |
| 4 | Sat 27 Feb 2021 | 240-2 v BarcelonaSevilla 0-2 Barcelona |
| 5 | Sat 6 Mar 2021 | 241-2 v ElcheElche 2-1 Sevilla |
| 6 | Sun 14 Mar 2021 | 241-0 v Real BetisSevilla 1-0 Real Betis |
| 7 | Wed 17 Mar 2021 | 242-0 v ElcheSevilla 2-0 Elche |
| 8 | Sat 20 Mar 2021 | 241-1 v Real ValladolidReal Valladolid 1-1 Sevilla |
| 9 | Sun 4 Apr 2021 | 241-0 v Atlético MadridSevilla 1-0 Atlético Madrid |
| 10 | Mon 12 Apr 2021 | 244-3 v Celta VigoCelta Vigo 3-4 Sevilla |
| 11 | Sun 18 Apr 2021 | 242-1 v Real SociedadReal Sociedad 1-2 Sevilla |
| 12 | Wed 21 Apr 2021 | 241-0 v LevanteLevante 0-1 Sevilla |
| 13 | Sun 25 Apr 2021 | 242-1 v GranadaSevilla 2-1 Granada |
| 14 | Mon 3 May 2021 | 240-1 v Athletic BilbaoSevilla 0-1 Athletic Bilbao |
| 15 | Sun 9 May 2021 | 242-2 v Real MadridReal Madrid 2-2 Sevilla |
| 16 | Wed 12 May 2021 | 241-0 v ValenciaSevilla 1-0 Valencia |
| 17 | Sun 16 May 2021 | 240-4 v VillarrealVillarreal 4-0 Sevilla |
| 18 | Sun 23 May 2021 | 241-0 v AlavésSevilla 1-0 Alavés |
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