| 1 | Tue 23 Jul | 292-0 v Shamrock RoversShamrock Rovers 0-2 Sparta Prague | UEFA Champions League Second Qualifying Round |
| 2 | Tue 30 Jul | 294-2 v Shamrock RoversSparta Prague 4-2 Shamrock Rovers | UEFA Champions League Second Qualifying Round |
| 3 | Tue 6 Aug | 29 1-1 v Steaua BucharestSparta Prague 1-1 Steaua Bucharest | UEFA Champions League Third Qualifying Round |
| 4 | Tue 27 Aug | 292-0 v Malmö FFSparta Prague 2-0 Malmö FF | UEFA Champions League Play-off |
| 5 | Wed 18 Sep | 293-0 v SV Red Bull SalzburgSparta Prague 3-0 SV Red Bull Salzburg | UEFA Champions League Matchday 1 |
| 6 | Tue 1 Oct | 291-1 v VfB StuttgartVfB Stuttgart 1-1 Sparta Prague | UEFA Champions League Matchday 2 |
| 7 | Wed 23 Oct | 290-5 v Manchester CityManchester City 5-0 Sparta Prague | UEFA Champions League Matchday 3 |
| 8 | Tue 26 Nov | 290-6 v Atlético MadridSparta Prague 0-6 Atlético Madrid | UEFA Champions League Matchday 5 |
| 9 | Wed 11 Dec | 292-4 v FeyenoordFeyenoord 4-2 Sparta Prague | UEFA Champions League Matchday 6 |
| 10 | Wed 22 Jan | 29 0-1 v Inter MilanSparta Prague 0-1 Inter Milan | UEFA Champions League Matchday 7 |
| 11 | Wed 29 Jan | 290-2 v Bayer 04 LeverkusenBayer 04 Leverkusen 2-0 Sparta Prague | UEFA Champions League Matchday 8 |
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