| 1 | 15/8/2021 | 6 1-0 v Manchester CityTottenham Hotspur 1-0 Manchester City | Premier League |
| 2 | 22/8/2021 | 61-0 v Wolverhampton WanderersWolverhampton Wanderers 0-1 Tottenham Hotspur | Premier League |
| 3 | 26/8/2021 | 63-0 v Paços de FerreiraTottenham Hotspur 3-0 Paços de Ferreira | UEFA Europa Conference League |
| 4 | 29/8/2021 | 61-0 v WatfordTottenham Hotspur 1-0 Watford | Premier League |
| 5 | 19/9/2021 | 60-3 v ChelseaTottenham Hotspur 0-3 Chelsea | Premier League |
| 6 | 22/9/2021 | 62-2 v Wolverhampton WanderersWolverhampton Wanderers 2-2 Tottenham Hotspur | Carabao Cup Third Round |
| 7 | 26/9/2021 | 61-3 v ArsenalArsenal 3-1 Tottenham Hotspur | Premier League |
| 8 | 30/9/2021 | 65-1 v Mura Murska SobotaTottenham Hotspur 5-1 Mura Murska Sobota | UEFA Europa Conference League |
| 9 | 3/10/2021 | 62-1 v Aston VillaTottenham Hotspur 2-1 Aston Villa | Premier League |
| 10 | 17/10/2021 | 63-2 v Newcastle UnitedNewcastle United 2-3 Tottenham Hotspur | Premier League |
| 11 | 21/10/2021 | 6 0-1 v VitesseVitesse 1-0 Tottenham Hotspur | UEFA Europa Conference League |
| 12 | 24/10/2021 | 60-1 v West Ham UnitedWest Ham United 1-0 Tottenham Hotspur | Premier League |
| 13 | 27/10/2021 | 61-0 v BurnleyBurnley 0-1 Tottenham Hotspur | Carabao Cup Round of 16 |
| 14 | 30/10/2021 | 60-3 v Manchester UnitedTottenham Hotspur 0-3 Manchester United | Premier League |
| 15 | 4/11/2021 | 63-2 v VitesseTottenham Hotspur 3-2 Vitesse | UEFA Europa Conference League |
| 16 | 7/11/2021 | 60-0 v EvertonEverton 0-0 Tottenham Hotspur | Premier League |
| 17 | 21/11/2021 | 62-1 v Leeds UnitedTottenham Hotspur 2-1 Leeds United | Premier League |
| 18 | 25/11/2021 | 61-2 v Mura Murska SobotaMura Murska Sobota 2-1 Tottenham Hotspur | UEFA Europa Conference League |
| 19 | 2/12/2021 | 62-0 v BrentfordTottenham Hotspur 2-0 Brentford | Premier League |
| 20 | 5/12/2021 | 63-0 v Norwich CityTottenham Hotspur 3-0 Norwich City | Premier League |
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