| 1 | Thu 10 Aug | 370-0 v Steaua BucharestSteaua Bucharest 0-0 FC Nordsjælland | UEFA Europa Conference League Third Qualifying Round |
| 2 | Thu 17 Aug | 37 2-0 v Steaua BucharestFC Nordsjælland 2-0 Steaua Bucharest | UEFA Europa Conference League Third Qualifying Round |
| 3 | Sun 3 Sep | 371-4 v Paris St GermainLyon 1-4 Paris St Germain | French Ligue 1 |
| 4 | Sun 17 Sep | 370-0 v Le HavreLyon 0-0 Le Havre | French Ligue 1 |
| 5 | Sat 23 Sep | 37 0-1 v BrestBrest 1-0 Lyon | French Ligue 1 |
| 6 | Sun 1 Oct | 370-2 v ReimsReims 2-0 Lyon | French Ligue 1 |
| 7 | Sun 8 Oct | 373-3 v LorientLyon 3-3 Lorient | French Ligue 1 |
| 8 | Sun 15 Oct | 170-2 v MexicoMexico 2-0 Ghana | International Friendly |
| 9 | Wed 18 Oct | 170-4 v USAUSA 4-0 Ghana | International Friendly |
| 10 | Sun 22 Oct | 371-2 v ClermontLyon 1-2 Clermont | French Ligue 1 |
| 11 | Sun 5 Nov | 371-1 v MetzLyon 1-1 Metz | French Ligue 1 |
| 12 | Sun 12 Nov | 371-0 v RennesRennes 0-1 Lyon | French Ligue 1 |
| 13 | Sun 26 Nov | 370-2 v LilleLyon 0-2 Lille | French Ligue 1 |
| 14 | Sat 2 Dec | 372-3 v LensLens 3-2 Lyon | French Ligue 1 |
| 15 | Wed 6 Dec | 370-3 v MarseilleMarseille 3-0 Lyon | French Ligue 1 |
| 16 | Sun 10 Dec | 373-0 v ToulouseLyon 3-0 Toulouse | French Ligue 1 |
| 17 | Fri 15 Dec | 371-0 v MonacoMonaco 0-1 Lyon | French Ligue 1 |
| 18 | Wed 20 Dec | 371-0 v NantesLyon 1-0 Nantes | French Ligue 1 |
| 19 | Sun 14 Jan | 241-2 v Cape VerdeGhana 1-2 Cape Verde | Africa Cup of Nations Group B |
| 20 | Fri 26 Jan | 37 2-3 v RennesLyon 2-3 Rennes | French Ligue 1 |
| 21 | Sun 4 Feb | 371-0 v MarseilleLyon 1-0 Marseille | French Ligue 1 |
| 22 | Sun 11 Feb | 372-1 v MontpellierMontpellier 1-2 Lyon | French Ligue 1 |
| 23 | Fri 16 Feb | 371-0 v NiceLyon 1-0 Nice | French Ligue 1 |
| 24 | Fri 23 Feb | 372-1 v MetzMetz 1-2 Lyon | French Ligue 1 |
| 25 | Sun 3 Mar | 370-3 v LensLyon 0-3 Lens | French Ligue 1 |
| 26 | Fri 15 Mar | 373-2 v ToulouseToulouse 2-3 Lyon | French Ligue 1 |
| 27 | Fri 22 Mar | 241-2 v NigeriaNigeria 2-1 Ghana | International Friendly |
| 28 | Sat 30 Mar | 371-1 v ReimsLyon 1-1 Reims | French Ligue 1 |
| 29 | Sun 7 Apr | 37 3-1 v NantesNantes 1-3 Lyon | French Ligue 1 |
| 30 | Sun 14 Apr | 374-3 v BrestLyon 4-3 Brest | French Ligue 1 |
| 31 | Sun 21 Apr | 371-4 v Paris St GermainParis St Germain 4-1 Lyon | French Ligue 1 |
| 32 | Sun 28 Apr | 373-2 v MonacoLyon 3-2 Monaco | French Ligue 1 |
| 33 | Mon 6 May | 37 4-3 v LilleLille 3-4 Lyon | French Ligue 1 |
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