| 1 | Sun 13 Aug | 8 2-1 v NantesNantes 1-2 Toulouse | French Ligue 1 |
| 2 | Sat 19 Aug | 81-1 v Paris St GermainToulouse 1-1 Paris St Germain | French Ligue 1 |
| 3 | Sun 27 Aug | 80-2 v StrasbourgStrasbourg 2-0 Toulouse | French Ligue 1 |
| 4 | Sun 3 Sep | 82-2 v ClermontToulouse 2-2 Clermont | French Ligue 1 |
| 5 | Sun 17 Sep | 80-0 v MarseilleMarseille 0-0 Toulouse | French Ligue 1 |
| 6 | Thu 21 Sep | 81-1 v Union Saint-GilloiseUnion Saint-Gilloise 1-1 Toulouse | UEFA Europa League Group E |
| 7 | Sun 24 Sep | 81-2 v LensLens 2-1 Toulouse | French Ligue 1 |
| 8 | Sun 1 Oct | 8 3-0 v MetzToulouse 3-0 Metz | French Ligue 1 |
| 9 | Thu 5 Oct | 81-0 v LASK LinzToulouse 1-0 LASK Linz | UEFA Europa League Group E |
| 10 | Sun 8 Oct | 81-1 v BrestBrest 1-1 Toulouse | French Ligue 1 |
| 11 | Sun 22 Oct | 81-1 v ReimsToulouse 1-1 Reims | French Ligue 1 |
| 12 | Thu 26 Oct | 81-5 v LiverpoolLiverpool 5-1 Toulouse | UEFA Europa League Group E |
| 13 | Sun 5 Nov | 81-2 v Le HavreToulouse 1-2 Le Havre | French Ligue 1 |
| 14 | Thu 9 Nov | 83-2 v LiverpoolToulouse 3-2 Liverpool | UEFA Europa League Group E |
| 15 | Sun 12 Nov | 81-1 v LilleLille 1-1 Toulouse | French Ligue 1 |
| 16 | Sun 26 Nov | 80-1 v NiceNice 1-0 Toulouse | French Ligue 1 |
| 17 | Thu 30 Nov | 8 0-0 v Union Saint-GilloiseToulouse 0-0 Union Saint-Gilloise | UEFA Europa League Group E |
| 18 | Sun 3 Dec | 8 1-1 v LorientToulouse 1-1 Lorient | French Ligue 1 |
| 19 | Sun 10 Dec | 8 0-3 v LyonLyon 3-0 Toulouse | French Ligue 1 |
| 20 | Thu 14 Dec | 82-1 v LASK LinzLASK Linz 1-2 Toulouse | UEFA Europa League Group E |
| 21 | Sun 17 Dec | 80-0 v RennesToulouse 0-0 Rennes | French Ligue 1 |
| 22 | Sun 14 Jan | 81-0 v MetzMetz 0-1 Toulouse | French Ligue 1 |
| 23 | Sun 28 Jan | 80-2 v LensToulouse 0-2 Lens | French Ligue 1 |
| 24 | Sun 4 Feb | 83-2 v ReimsReims 2-3 Toulouse | French Ligue 1 |
| 25 | Sun 11 Feb | 8 1-2 v NantesToulouse 1-2 Nantes | French Ligue 1 |
| 26 | Thu 15 Feb | 81-2 v BenficaBenfica 2-1 Toulouse | UEFA Europa League |
| 27 | Sun 18 Feb | 82-1 v MonacoMonaco 1-2 Toulouse | French Ligue 1 |
| 28 | Thu 22 Feb | 80-0 v BenficaToulouse 0-0 Benfica | UEFA Europa League |
| 29 | Sun 25 Feb | 8 3-1 v LilleToulouse 3-1 Lille | French Ligue 1 |
| 30 | Sun 3 Mar | 82-1 v NiceToulouse 2-1 Nice | French Ligue 1 |
| 31 | Sun 10 Mar | 80-1 v Le HavreLe Havre 1-0 Toulouse | French Ligue 1 |
| 32 | Fri 15 Mar | 82-3 v LyonToulouse 2-3 Lyon | French Ligue 1 |
| 33 | Tue 26 Mar | 251-0 v Republic of IrelandRepublic of Ireland 0-1 Switzerland | International Friendly |
| 34 | Sun 31 Mar | 8 3-0 v ClermontClermont 0-3 Toulouse | French Ligue 1 |
| 35 | Sun 7 Apr | 80-0 v StrasbourgToulouse 0-0 Strasbourg | French Ligue 1 |
| 36 | Sun 21 Apr | 82-2 v MarseilleToulouse 2-2 Marseille | French Ligue 1 |
| 37 | Sun 28 Apr | 8 2-1 v LorientLorient 1-2 Toulouse | French Ligue 1 |
| 38 | Fri 3 May | 81-2 v MontpellierToulouse 1-2 Montpellier | French Ligue 1 |
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