| 1 | Sun 15 Aug 2021 | 950-1 v FenerbahçeAdana Demirspor 0-1 Fenerbahçe |
| 2 | Fri 20 Aug 2021 | 951-1 v KayserisporKayserispor 1-1 Adana Demirspor |
| 3 | Sat 11 Sep 2021 | 950-4 v Fatih KaragümrükFatih Karagümrük 4-0 Adana Demirspor |
| 4 | Sat 18 Sep 2021 | 953-1 v Çaykur RizesporAdana Demirspor 3-1 Çaykur Rizespor |
| 5 | Tue 21 Sep 2021 | 953-3 v BeşiktaşBeşiktaş 3-3 Adana Demirspor |
| 6 | Sat 25 Sep 2021 | 954-0 v Gazişehir GaziantepAdana Demirspor 4-0 Gazişehir Gaziantep |
| 7 | Fri 1 Oct 2021 | 952-1 v AntalyasporAntalyaspor 1-2 Adana Demirspor |
| 8 | Sat 16 Oct 2021 | 950-2 v Yeni MalatyasporAdana Demirspor 0-2 Yeni Malatyaspor |
| 9 | Sun 24 Oct 2021 | 951-1 v SivassporSivasspor 1-1 Adana Demirspor |
| 10 | Mon 1 Nov 2021 | 951-2 v İstanbul Başakşehirİstanbul Başakşehir 2-1 Adana Demirspor |
| 11 | Sun 7 Nov 2021 | 951-0 v HataysporAdana Demirspor 1-0 Hatayspor |
| 12 | Sun 21 Nov 2021 | 953-1 v AltayAltay 1-3 Adana Demirspor |
| 13 | Fri 26 Nov 2021 | 95 0-0 v Kasımpaşa SKAdana Demirspor 0-0 Kasımpaşa SK |
| 14 | Sat 4 Dec 2021 | 950-2 v TrabzonsporTrabzonspor 2-0 Adana Demirspor |
| 15 | Sun 12 Dec 2021 | 951-0 v GiresunsporAdana Demirspor 1-0 Giresunspor |
| 16 | Sun 26 Dec 2021 | 951-1 v Göztepe SKGöztepe SK 1-1 Adana Demirspor |
| 17 | Sat 19 Mar 2022 | 952-1 v İstanbul BaşakşehirAdana Demirspor 2-1 İstanbul Başakşehir |
| 18 | Mon 4 Apr 2022 | 950-0 v HataysporHatayspor 0-0 Adana Demirspor |
| 19 | Sun 10 Apr 2022 | 953-1 v AltayAdana Demirspor 3-1 Altay |
| 20 | Sun 17 Apr 2022 | 95 0-4 v Kasımpaşa SKKasımpaşa SK 4-0 Adana Demirspor |
| 21 | Sat 23 Apr 2022 | 951-3 v TrabzonsporAdana Demirspor 1-3 Trabzonspor |
| 22 | Fri 29 Apr 2022 | 950-2 v GiresunsporGiresunspor 2-0 Adana Demirspor |
| 23 | Sat 7 May 2022 | 951-2 v AlanyasporAdana Demirspor 1-2 Alanyaspor |
| 24 | Mon 16 May 2022 | 952-3 v GalatasarayGalatasaray 3-2 Adana Demirspor |
| 25 | Sun 22 May 2022 | 957-0 v Göztepe SKAdana Demirspor 7-0 Göztepe SK |
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