| 1 | Sat 12 Aug | 991-1 v KonyasporKonyaspor 1-1 İstanbulspor |
| 2 | Fri 18 Aug | 991-1 v Kayserisporİstanbulspor 1-1 Kayserispor |
| 3 | Sun 17 Sep | 990-2 v İstanbul Başakşehirİstanbulspor 0-2 İstanbul Başakşehir |
| 4 | Fri 22 Sep | 990-2 v Gazişehir GaziantepGazişehir Gaziantep 2-0 İstanbulspor |
| 5 | Sun 22 Oct | 992-1 v Ankaragücüİstanbulspor 2-1 Ankaragücü |
| 6 | Fri 27 Oct | 991-3 v Kasımpaşa SKKasımpaşa SK 3-1 İstanbulspor |
| 7 | Sat 4 Nov | 992-4 v Pendiksporİstanbulspor 2-4 Pendikspor |
| 8 | Sat 25 Nov | 992-1 v Hataysporİstanbulspor 2-1 Hatayspor |
| 9 | Fri 1 Dec | 990-3 v Fatih KaragümrükFatih Karagümrük 3-0 İstanbulspor |
| 10 | Sun 10 Dec | 990-1 v Alanyasporİstanbulspor 0-1 Alanyaspor |
| 11 | Tue 19 Dec | 990-3 v Trabzonsporİstanbulspor 0-3 Trabzonspor |
| 12 | Sat 23 Dec | 990-1 v SivassporSivasspor 1-0 İstanbulspor |
| 13 | Sun 7 Jan | 991-5 v Fenerbahçeİstanbulspor 1-5 Fenerbahçe |
| 14 | Wed 10 Jan | 992-2 v Adana DemirsporAdana Demirspor 2-2 İstanbulspor |
| 15 | Sun 14 Jan | 990-0 v Konyasporİstanbulspor 0-0 Konyaspor |
| 16 | Sat 17 Feb | 992-2 v AntalyasporAntalyaspor 2-2 İstanbulspor |
| 17 | Sun 25 Feb | 990-2 v Beşiktaşİstanbulspor 0-2 Beşiktaş |
| 18 | Sat 2 Mar | 991-1 v AnkaragücüAnkaragücü 1-1 İstanbulspor |
| 19 | Sun 10 Mar | 991-2 v Kasımpaşa SKİstanbulspor 1-2 Kasımpaşa SK |
| 20 | Fri 15 Mar | 990-1 v PendiksporPendikspor 1-0 İstanbulspor |
| 21 | Tue 2 Apr | 990-4 v Çaykur Rizesporİstanbulspor 0-4 Çaykur Rizespor |
| 22 | Sun 14 Apr | 993-0 v HataysporHatayspor 0-3 İstanbulspor |
| 23 | Sat 20 Apr | 991-2 v Fatih Karagümrükİstanbulspor 1-2 Fatih Karagümrük |
| 24 | Sun 28 Apr | 990-6 v AlanyasporAlanyaspor 6-0 İstanbulspor |
| 25 | Sun 12 May | 990-3 v TrabzonsporTrabzonspor 3-0 İstanbulspor |
| 26 | Fri 17 May | 991-3 v Sivassporİstanbulspor 1-3 Sivasspor |
| 27 | Sun 26 May | 990-6 v FenerbahçeFenerbahçe 6-0 İstanbulspor |
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