| 1 | Fri 2 Aug | 43-1 v Germinal BeerschotUnion Saint-Gilloise 3-1 Germinal Beerschot | Belgian First Division A |
| 2 | Wed 7 Aug | 41-3 v Slavia PragueSlavia Prague 3-1 Union Saint-Gilloise | UEFA Champions League Third Qualifying Round |
| 3 | Sat 10 Aug | 43-4 v KVC WesterloKVC Westerlo 4-3 Union Saint-Gilloise | Belgian First Division A |
| 4 | Tue 13 Aug | 40-1 v Slavia PragueUnion Saint-Gilloise 0-1 Slavia Prague | UEFA Champions League Third Qualifying Round |
| 5 | Sun 25 Aug | 40-0 v Sint-Truidense VVSint-Truidense VV 0-0 Union Saint-Gilloise | Belgian First Division A |
| 6 | Sun 15 Sep | 40-2 v Royal AntwerpRoyal Antwerp 2-0 Union Saint-Gilloise | Belgian First Division A |
| 7 | Fri 20 Sep | 40-0 v Standard LiègeStandard Liège 0-0 Union Saint-Gilloise | Belgian First Division A |
| 8 | Thu 26 Sep | 41-2 v FenerbahçeFenerbahçe 2-1 Union Saint-Gilloise | UEFA Europa League Matchday 1 |
| 9 | Sun 29 Sep | 43-0 v KV KortrijkUnion Saint-Gilloise 3-0 KV Kortrijk | Belgian First Division A |
| 10 | Thu 3 Oct | 40-0 v FK Bodø/GlimtUnion Saint-Gilloise 0-0 FK Bodø/Glimt | UEFA Europa League Matchday 2 |
| 11 | Sun 6 Oct | 41-1 v Club BruggeClub Brugge 1-1 Union Saint-Gilloise | Belgian First Division A |
| 12 | Sat 19 Oct | 40-0 v KAA GentUnion Saint-Gilloise 0-0 KAA Gent | Belgian First Division A |
| 13 | Thu 24 Oct | 40-1 v FC MidtjyllandFC Midtjylland 1-0 Union Saint-Gilloise | UEFA Europa League Matchday 3 |
| 14 | Sun 27 Oct | 41-3 v Cercle BruggeUnion Saint-Gilloise 1-3 Cercle Brugge | Belgian First Division A |
| 15 | Sun 24 Nov | 41-1 v Oud-Heverlee LeuvenOud-Heverlee Leuven 1-1 Union Saint-Gilloise | Belgian First Division A |
| 16 | Thu 28 Nov | 41-0 v FC TwenteFC Twente 0-1 Union Saint-Gilloise | UEFA Europa League Matchday 5 |
| 17 | Sun 8 Dec | 40-0 v Cercle BruggeCercle Brugge 0-0 Union Saint-Gilloise | Belgian First Division A |
| 18 | Thu 23 Jan | 42-1 v Sporting BragaUnion Saint-Gilloise 2-1 Sporting Braga | UEFA Europa League Matchday 7 |
| 19 | Thu 30 Jan | 41-2 v RangersRangers 2-1 Union Saint-Gilloise | UEFA Europa League Matchday 8 |
| 20 | Sun 2 Feb | 42-1 v Sint-Truidense VVUnion Saint-Gilloise 2-1 Sint-Truidense VV | Belgian First Division A |
| 21 | Sun 9 Feb | 42-1 v KV KortrijkKV Kortrijk 1-2 Union Saint-Gilloise | Belgian First Division A |
| 22 | Thu 13 Feb | 40-2 v AjaxUnion Saint-Gilloise 0-2 Ajax | UEFA Europa League Play-off Knockout Round |
| 23 | Sun 16 Feb | 40-1 v MechelenUnion Saint-Gilloise 0-1 Mechelen | Belgian First Division A |
| 24 | Thu 20 Feb | 42-1 v AjaxAjax 1-2 Union Saint-Gilloise | UEFA Europa League Play-off Knockout Round |
| 25 | Sun 23 Feb | 42-0 v RSC AnderlechtRSC Anderlecht 0-2 Union Saint-Gilloise | Belgian First Division A |
| 26 | Sat 1 Mar | 44-1 v FCV Dender EHUnion Saint-Gilloise 4-1 FCV Dender EH | Belgian First Division A |
| 27 | Sun 9 Mar | 4 3-0 v Standard LiègeUnion Saint-Gilloise 3-0 Standard Liège | Belgian First Division A |
| 28 | Sat 15 Mar | 41-2 v KRC GenkKRC Genk 2-1 Union Saint-Gilloise | Belgian First Division A |
| 29 | Sat 29 Mar | 45-1 v Royal AntwerpUnion Saint-Gilloise 5-1 Royal Antwerp | Belgian First Division A Play-off |
| 30 | Sat 5 Apr | 43-0 v KAA GentKAA Gent 0-3 Union Saint-Gilloise | Belgian First Division A Play-off |
| 31 | Sun 20 Apr | 42-1 v KRC GenkKRC Genk 1-2 Union Saint-Gilloise | Belgian First Division A Play-off |
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