| 1 | Sat 14 Aug 2021 | 171-0 v VfL BochumVfL Wolfsburg 1-0 VfL Bochum | German Bundesliga |
| 2 | Sat 21 Aug 2021 | 172-1 v Hertha BerlinHertha Berlin 1-2 VfL Wolfsburg | German Bundesliga |
| 3 | Sun 29 Aug 2021 | 171-0 v RB LeipzigVfL Wolfsburg 1-0 RB Leipzig | German Bundesliga |
| 4 | Sat 11 Sep 2021 | 172-0 v Greuther FürthGreuther Fürth 0-2 VfL Wolfsburg | German Bundesliga |
| 5 | Tue 14 Sep 2021 | 170-0 v LilleLille 0-0 VfL Wolfsburg | UEFA Champions League Group G |
| 6 | Sat 25 Sep 2021 | 171-3 v 1899 Hoffenheim1899 Hoffenheim 3-1 VfL Wolfsburg | German Bundesliga |
| 7 | Sat 2 Oct 2021 | 171-3 v Borussia MönchengladbachVfL Wolfsburg 1-3 Borussia Mönchengladbach | German Bundesliga |
| 8 | Sat 16 Oct 2021 | 170-2 v 1. FC Union Berlin1. FC Union Berlin 2-0 VfL Wolfsburg | German Bundesliga |
| 9 | Sat 23 Oct 2021 | 170-2 v SC FreiburgVfL Wolfsburg 0-2 SC Freiburg | German Bundesliga |
| 10 | Sat 30 Oct 2021 | 172-0 v Bayer 04 LeverkusenBayer 04 Leverkusen 0-2 VfL Wolfsburg | German Bundesliga |
| 11 | Sat 20 Nov 2021 | 172-2 v Arminia BielefeldArminia Bielefeld 2-2 VfL Wolfsburg | German Bundesliga |
| 12 | Tue 23 Nov 2021 | 170-2 v SevillaSevilla 2-0 VfL Wolfsburg | UEFA Champions League Group G |
| 13 | Sat 27 Nov 2021 | 171-3 v Borussia DortmundVfL Wolfsburg 1-3 Borussia Dortmund | German Bundesliga |
| 14 | Sat 4 Dec 2021 | 170-3 v Mainz 05Mainz 05 3-0 VfL Wolfsburg | German Bundesliga |
| 15 | Sun 9 Jan 2022 | 170-1 v VfL BochumVfL Bochum 1-0 VfL Wolfsburg | German Bundesliga |
| 16 | Sun 23 Jan 2022 | 170-2 v RB LeipzigRB Leipzig 2-0 VfL Wolfsburg | German Bundesliga |
| 17 | Sun 6 Feb 2022 | 174-1 v Greuther FürthVfL Wolfsburg 4-1 Greuther Fürth | German Bundesliga |
| 18 | Sat 12 Feb 2022 | 172-0 v Eintracht FrankfurtEintracht Frankfurt 0-2 VfL Wolfsburg | German Bundesliga |
| 19 | Sat 19 Feb 2022 | 17 1-2 v 1899 HoffenheimVfL Wolfsburg 1-2 1899 Hoffenheim | German Bundesliga |
| 20 | Sat 26 Feb 2022 | 17 2-2 v Borussia MönchengladbachBorussia Mönchengladbach 2-2 VfL Wolfsburg | German Bundesliga |
| 21 | Sat 12 Mar 2022 | 172-3 v SC FreiburgSC Freiburg 3-2 VfL Wolfsburg | German Bundesliga |
| 22 | Fri 22 Apr 2022 | 175-0 v Mainz 05VfL Wolfsburg 5-0 Mainz 05 | German Bundesliga |
| 23 | Sat 30 Apr 2022 | 171-1 v VfB StuttgartVfB Stuttgart 1-1 VfL Wolfsburg | German Bundesliga |
| 24 | Sat 14 May 2022 | 172-2 v Bayern MunichVfL Wolfsburg 2-2 Bayern Munich | German Bundesliga |
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