| 1 | Thu 8 Aug | 312-1 v Kryvbas KRKryvbas KR 1-2 Viktoria Plzen | UEFA Europa League Third Qualifying Round |
| 2 | Thu 15 Aug | 311-0 v Kryvbas KRViktoria Plzen 1-0 Kryvbas KR | UEFA Europa League Third Qualifying Round |
| 3 | Thu 22 Aug | 311-0 v Heart of MidlothianViktoria Plzen 1-0 Heart of Midlothian | UEFA Europa League Play-off |
| 4 | Thu 29 Aug | 311-0 v Heart of MidlothianHeart of Midlothian 0-1 Viktoria Plzen | UEFA Europa League Play-off |
| 5 | Thu 26 Sep | 313-3 v Eintracht FrankfurtEintracht Frankfurt 3-3 Viktoria Plzen | UEFA Europa League Matchday 1 |
| 6 | Thu 3 Oct | 31 0-0 v LudogoretsViktoria Plzen 0-0 Ludogorets | UEFA Europa League Matchday 2 |
| 7 | Thu 24 Oct | 312-2 v PAOK FCPAOK FC 2-2 Viktoria Plzen | UEFA Europa League Matchday 3 |
| 8 | Thu 7 Nov | 312-1 v Real SociedadViktoria Plzen 2-1 Real Sociedad | UEFA Europa League Matchday 4 |
| 9 | Thu 28 Nov | 312-1 v Dynamo KievDynamo Kiev 1-2 Viktoria Plzen | UEFA Europa League Matchday 5 |
| 10 | Thu 12 Dec | 311-2 v Manchester UnitedViktoria Plzen 1-2 Manchester United | UEFA Europa League Matchday 6 |
| 11 | Thu 23 Jan | 312-0 v RSC AnderlechtViktoria Plzen 2-0 RSC Anderlecht | UEFA Europa League Matchday 7 |
| 12 | Thu 30 Jan | 311-3 v Athletic BilbaoAthletic Bilbao 3-1 Viktoria Plzen | UEFA Europa League Matchday 8 |
| 13 | Thu 13 Feb | 310-1 v Ferencvárosi TCFerencvárosi TC 1-0 Viktoria Plzen | UEFA Europa League Play-off Knockout Round |
| 14 | Thu 20 Feb | 313-0 v Ferencvárosi TCViktoria Plzen 3-0 Ferencvárosi TC | UEFA Europa League Play-off Knockout Round |
| 15 | Thu 6 Mar | 311-2 v LazioViktoria Plzen 1-2 Lazio | UEFA Europa League Round of 16 |
| 16 | Thu 13 Mar | 311-1 v LazioLazio 1-1 Viktoria Plzen | UEFA Europa League Round of 16 |
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