| 1 | 4/10/2020 | 5 3-0 v Leicester CityLeicester City 0-3 West Ham United | Premier League |
| 2 | 18/10/2020 | 53-3 v Tottenham HotspurTottenham Hotspur 3-3 West Ham United | Premier League |
| 3 | 24/10/2020 | 5 1-1 v Manchester CityWest Ham United 1-1 Manchester City | Premier League |
| 4 | 31/10/2020 | 51-2 v LiverpoolLiverpool 2-1 West Ham United | Premier League |
| 5 | 7/11/2020 | 51-0 v FulhamWest Ham United 1-0 Fulham | Premier League |
| 6 | 22/11/2020 | 51-0 v Sheffield UnitedSheffield United 0-1 West Ham United | Premier League |
| 7 | 30/11/2020 | 52-1 v Aston VillaWest Ham United 2-1 Aston Villa | Premier League |
| 8 | 5/12/2020 | 51-3 v Manchester UnitedWest Ham United 1-3 Manchester United | Premier League |
| 9 | 11/12/2020 | 52-1 v Leeds UnitedLeeds United 1-2 West Ham United | Premier League |
| 10 | 16/12/2020 | 51-1 v Crystal PalaceWest Ham United 1-1 Crystal Palace | Premier League |
| 11 | 21/12/2020 | 50-3 v ChelseaChelsea 3-0 West Ham United | Premier League |
| 12 | 27/12/2020 | 52-2 v Brighton & Hove AlbionWest Ham United 2-2 Brighton & Hove Albion | Premier League |
| 13 | 29/12/2020 | 50-0 v SouthamptonSouthampton 0-0 West Ham United | Premier League |
| 14 | 1/1/2021 | 51-0 v EvertonEverton 0-1 West Ham United | Premier League |
| 15 | 11/1/2021 | 51-0 v Stockport CountyStockport County 0-1 West Ham United | Emirates FA Cup Third Round |
| 16 | 16/1/2021 | 51-0 v BurnleyWest Ham United 1-0 Burnley | Premier League |
| 17 | 19/1/2021 | 52-1 v West Bromwich AlbionWest Ham United 2-1 West Bromwich Albion | Premier League |
| 18 | 23/1/2021 | 54-0 v Doncaster RoversWest Ham United 4-0 Doncaster Rovers | Emirates FA Cup Fourth Round |
| 19 | 26/1/2021 | 53-2 v Crystal PalaceCrystal Palace 2-3 West Ham United | Premier League |
| 20 | 31/1/2021 | 51-3 v LiverpoolWest Ham United 1-3 Liverpool | Premier League |
| 21 | 3/2/2021 | 53-1 v Aston VillaAston Villa 1-3 West Ham United | Premier League |
| 22 | 6/2/2021 | 50-0 v FulhamFulham 0-0 West Ham United | Premier League |
| 23 | 9/2/2021 | 50-1 v Manchester UnitedManchester United 1-0 West Ham United | Emirates FA Cup Fifth Round |
| 24 | 15/2/2021 | 53-0 v Sheffield UnitedWest Ham United 3-0 Sheffield United | Premier League |
| 25 | 21/2/2021 | 52-1 v Tottenham HotspurWest Ham United 2-1 Tottenham Hotspur | Premier League |
| 26 | 27/2/2021 | 51-2 v Manchester CityManchester City 2-1 West Ham United | Premier League |
| 27 | 8/3/2021 | 52-0 v Leeds UnitedWest Ham United 2-0 Leeds United | Premier League |
| 28 | 14/3/2021 | 50-1 v Manchester UnitedManchester United 1-0 West Ham United | Premier League |
| 29 | 21/3/2021 | 5 3-3 v ArsenalWest Ham United 3-3 Arsenal | Premier League |
| 30 | 5/4/2021 | 53-2 v Wolverhampton WanderersWolverhampton Wanderers 2-3 West Ham United | Premier League |
| 31 | 11/4/2021 | 53-2 v Leicester CityWest Ham United 3-2 Leicester City | Premier League |
| 32 | 17/4/2021 | 52-3 v Newcastle UnitedNewcastle United 3-2 West Ham United | Premier League |
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