| 1 | Sat 19 Aug | 141-2 v SC Freiburg1899 Hoffenheim 1-2 SC Freiburg |
| 2 | Sat 26 Aug | 143-2 v 1 FC Heidenheim1 FC Heidenheim 2-3 1899 Hoffenheim |
| 3 | Sat 2 Sep | 143-1 v VfL Wolfsburg1899 Hoffenheim 3-1 VfL Wolfsburg |
| 4 | Sat 16 Sep | 143-1 v 1 FC Köln1 FC Köln 1-3 1899 Hoffenheim |
| 5 | Sat 23 Sep | 142-0 v 1 FC Union Berlin1 FC Union Berlin 0-2 1899 Hoffenheim |
| 6 | Fri 29 Sep | 141-3 v Borussia Dortmund1899 Hoffenheim 1-3 Borussia Dortmund |
| 7 | Sat 7 Oct | 143-2 v Werder BremenWerder Bremen 2-3 1899 Hoffenheim |
| 8 | Sat 21 Oct | 141-3 v Eintracht Frankfurt1899 Hoffenheim 1-3 Eintracht Frankfurt |
| 9 | Sat 28 Oct | 143-2 v VfB StuttgartVfB Stuttgart 2-3 1899 Hoffenheim |
| 10 | Sat 4 Nov | 142-3 v Bayer 04 Leverkusen1899 Hoffenheim 2-3 Bayer 04 Leverkusen |
| 11 | Sat 11 Nov | 141-1 v FC AugsburgFC Augsburg 1-1 1899 Hoffenheim |
| 12 | Sun 26 Nov | 141-1 v Mainz 051899 Hoffenheim 1-1 Mainz 05 |
| 13 | Sat 2 Dec | 141-2 v Borussia MönchengladbachBorussia Mönchengladbach 2-1 1899 Hoffenheim |
| 14 | Sat 16 Dec | 141-3 v RB LeipzigRB Leipzig 3-1 1899 Hoffenheim |
| 15 | Tue 19 Dec | 143-3 v Darmstadt 981899 Hoffenheim 3-3 Darmstadt 98 |
| 16 | Fri 12 Jan | 140-3 v Bayern MunichBayern Munich 3-0 1899 Hoffenheim |
| 17 | Sat 20 Jan | 142-3 v SC FreiburgSC Freiburg 3-2 1899 Hoffenheim |
| 18 | Sat 27 Jan | 141-1 v 1 FC Heidenheim1899 Hoffenheim 1-1 1 FC Heidenheim |
| 19 | Sun 4 Feb | 142-2 v VfL WolfsburgVfL Wolfsburg 2-2 1899 Hoffenheim |
| 20 | Sun 11 Feb | 141-1 v 1 FC Köln1899 Hoffenheim 1-1 1 FC Köln |
| 21 | Sat 17 Feb | 140-1 v 1 FC Union Berlin1899 Hoffenheim 0-1 1 FC Union Berlin |
| 22 | Sun 25 Feb | 143-2 v Borussia DortmundBorussia Dortmund 2-3 1899 Hoffenheim |
| 23 | Sun 3 Mar | 142-1 v Werder Bremen1899 Hoffenheim 2-1 Werder Bremen |
| 24 | Sun 10 Mar | 141-3 v Eintracht FrankfurtEintracht Frankfurt 3-1 1899 Hoffenheim |
| 25 | Sat 16 Mar | 140-3 v VfB Stuttgart1899 Hoffenheim 0-3 VfB Stuttgart |
| 26 | Sat 30 Mar | 141-2 v Bayer 04 LeverkusenBayer 04 Leverkusen 2-1 1899 Hoffenheim |
| 27 | Sun 7 Apr | 143-1 v FC Augsburg1899 Hoffenheim 3-1 FC Augsburg |
| 28 | Sat 13 Apr | 141-4 v Mainz 05Mainz 05 4-1 1899 Hoffenheim |
| 29 | Sat 20 Apr | 144-3 v Borussia Mönchengladbach1899 Hoffenheim 4-3 Borussia Mönchengladbach |
| 30 | Fri 26 Apr | 142-3 v VfL BochumVfL Bochum 3-2 1899 Hoffenheim |
| 31 | Fri 3 May | 141-1 v RB Leipzig1899 Hoffenheim 1-1 RB Leipzig |
| 32 | Sun 12 May | 146-0 v Darmstadt 98Darmstadt 98 0-6 1899 Hoffenheim |
| 33 | Sat 18 May | 144-2 v Bayern Munich1899 Hoffenheim 4-2 Bayern Munich |
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